Millions of people struggle with medical indebtedness. Millions more are thought to forgo care or put off treatment, hoping to avoid medical bills. The nonprofit media, Kaiser Health News, published extensive surveys on medical debt in 2022. According to National Public Radio (NPR):
Category: Consumer-Driven Health Care
Tuesday Links
- Does lead in the air affect learning in school?
- Stephen Pinker: The development of artificial general intelligence is incoherent and not achievable.
- Increased access to physicians results in better health – at least in Nigeria.
- If the estimates from Statista Consumer Marketing Research are accurate, from 2020 to 2022 the world bought 928 billion masks at a cost of $389 billion — most of them made of plastic. I wonder how much of the plastic ended up in the ocean?
- Oops. The Inflation Reduction Act will increase taxes on millions of Americans earning less than $400,000, despite the president’s repeated promises not to do that. And that’s only for starters.
Monday Links
- The IRA bill threatens orphan drugs.
- Study finds links between the popular zero-calorie sugar substitute erythritol and an increased risk of cardiovascular events, including heart attack and stroke.
- But the study has limits. (NYT)
- Death on demand: Canadian euthanasia is killing about 27 people a day on average — over 10,000 a year.
“Escape >From the Lab” is Not Just Theory
“What this means, in non-technical language, is that Shi set out to create novel coronaviruses with the highest possible infectivity for human cells. Her plan was to take genes that coded for spike proteins possessing a variety of measured affinities for human cells, ranging from high to low. She would insert these spike genes one by one into the backbone of a number of viral genomes (“reverse genetics” and “infectious clone technology”), creating a series of chimeric viruses. These chimeric viruses would then be tested for their ability to attack human cell cultures (“in vitro”) and humanized mice (“in vivo”). And this information would help predict the likelihood of “spillover,” the jump of a coronavirus from bats to people.
“The methodical approach was designed to find the best combination of coronavirus backbone and spike protein for infecting human cells. The approach could have generated SARS2-like viruses, and indeed may have created the SARS2 virus itself with the right combination of virus backbone and spike protein.
“It cannot yet be stated that Shi did or did not generate SARS2 in her lab because her records have been sealed, but it seems she was certainly on the right track to have done so. “It is clear that the Wuhan Institute of Virology was systematically constructing novel chimeric coronaviruses and was assessing their ability to infect human cells and human-ACE2-expressing mice,” says Richard H. Ebright, a molecular biologist at Rutgers University and leading expert on biosafety.