We conservatively find that the IRA’s policy to set prices at 9 years after market entry for select small molecule drugs will reduce their expected revenues in the U.S. market by 8.0%, which implies a reduction in R&D investment of almost 12.3%, or $232.1 billion over 20 years. Over the same time frame, we conclude that there will be 188 fewer small molecule treatments, including 79 fewer new small molecule drugs and 109 fewer post-approval indications for these drugs. We find that this forgone innovation is expected to lead to 116.0 million life years lost due to the missed opportunities to improve health.
Author: John C. Goodman
Wednesday Links
- Study: Too much niacin may increase the risk of cardiovascular disease. It helps me combat vertigo.
- A person younger than 18 shot and killed another child somewhere in the United States once a day, every day — on average last year. (NYT)
- Study: Teens turn to drugs because of stress.
- Are cancer patients being overdosed with cancer drugs?
- Among millions immunized, largest Covid vaccine study yet finds links to health conditions.
Tuesday Links
- Under no-give, no-take, people who sign their organ donor cards get priority should they one day need an organ.
- Social spending as a percentage of GDP has increased in basically every country that we have data for over time.
- Is there a relationship between penis length and IQ? HT: Tyler
- Masturbation is healthy.
- Why are so many pedestrians getting killed? Are cell phones to blame? (NYT)
Monday Links
- Suicide, anxiety, and depression numbers are rising among teens. Is social media the problem? Observation: “Every child uses social media but not every child has a mental health problem.”
- Are children the victims of Medicaid expansion?
- Several studies have linked Medicaid expansion to longer wait times for appointments, slower ambulance response times, and greater delays in the emergency room.
- The bipartisan tax deal increases both marriage bonuses and marriage penalties.
- CBO: Budget deficits will average $2.0 trillion per year – or 5.7 percent of GDP – over the next decade.
- How can a silk patch replace a hypodermic needle?