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The Goodman Institute Health Blog

Category: Experts

The FDA is Increasingly Skeptical of Therapies for Rare Diseases

Posted on March 7, 2026March 6, 2026 by Devon Herrick

The FDA under Trump has consistently maintained its stated goal of removing bureaucratic obstacles to drug approval. FDA commissioner, Marty Makary, announced steps to speed the approval of new drugs, including allowing one well-designed clinical trial rather than two or more trials to show efficacy. Yet, drug companies continue to claim inconsistent guidelines, endpoints changed and a skeptical agency when it comes to rare disease therapies. Recently drugmakers have complained the FDA moved the goalposts, after agreeing to them. 

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Have we kissed the Fourth Amendment goodbye?

Posted on January 28, 2026January 27, 2026 by Merrill Matthews

The Democratic midterm campaign ads will write themselves. Images of multiple masked government agents, decked out in tactical gear, weapons drawn, restraining an individual or “perp walking” someone half-naked from a house in the snow. They will show protesters, who look like average Americans, shouting and filming. These pictures are creating very negative voter perceptions and raising serious questions, even if the Trump administration did everything right.

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Wednesday Links

Posted on January 28, 2026January 27, 2026 by John C. Goodman
  • More than half of all Americans take vitamin supplements. (Bloomberg)
  • 41 percent of Gen Z and 47 percent of millennials who are engaged or have been married said they entered a prenup.
  • The “prescribing cascade”: one drug causes side effects that doctors mistake for a new disease, triggering another prescription that creates its own problems, leaving people trapped in a sea of unnecessary and potentially harmful medications.
  • A growing body of quantitative research indicates that some school-based mental health interventions actually create mental health problems.
  • Why is the government under Trump investing so much money in so many private companies?
  • Hospital expenses per adjusted inpatient day vary widely across states and ownership types, with costs ranging from under $700 to more than $6,000.
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Attorney General Bondi wants a letter of support from me. No way.

Posted on January 20, 2026January 20, 2026 by Merrill Matthews

Attorney General Pam Bondi is reportedly hitting a rough spot with President Trump. So, Department of Justice employees have started reaching out to various conservative organizations seeking praise and support. One Department of Justice staffer reached out to me. It’s not going to happen.

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For many years, our health care blog was the only free enterprise health policy blog on the internet. Then, when the NCPA closed its doors, the health blog stopped as well.

During this five-year hiatus no one else has come forward to claim the space. So, my colleagues and I have decided to restart the blog in connection with the Goodman Institute. We invite you and others to use this forum to share your views.

John C. Goodman,

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